Galmed子公司Colospan完成32例结直肠手术组织评估技术可行性研究

- The prospective, single-arm study enrolled 32 colorectal cancer patients at three leading clinical centers in Israel. The primary objective was to demonstrate feasibility of intraoperative quantitative measurement of colon tissue quality.
- The study establishes the clinical foundation for novel intraoperative tissue assessment technology, with an aim to expand Colospan's product pipeline with a second technology platform for Colorectal Surgery.
- The new technology platform, which complements Colospan's CG-100 intraluminal bypass device, is designed to advance Galmed's strategy to build a leading innovative medtech and biotech company addressing unmet needs in GI oncology and colorectal surgery.
RAMAT-GAN, Israel, Aug. 19, 2026 /PRNewswire/ -- Colospan Ltd., a wholly owned subsidiary of Galmed Pharmaceuticals Ltd. (NASDAQ: GLMD), today announced the successful completion of a feasibility study supporting the development of a novel intraoperative colon tissue quality assessment platform. The technology represents Colospan's second platform, expanding the innovation pipeline beyond its lead product, CG-100, and reinforcing Galmed's strategy of building a diversified portfolio of technologies addressing significant unmet needs in colorectal surgery.
The feasibility study enrolled 32 colorectal cancer patients undergoing elective colorectal surgery at three leading Israeli medical centers. The study successfully demonstrated that quantitative measurement of colon tissue compliance is technically feasible using a novel ex-vivo methodology. Successful measurements obtained in all 32 patients with no measurement failures or procedure-related technical issues. These results establish the clinical foundation for continued development of an intraoperative device intended to objectively evaluate colon tissue quality during surgery.
The new platform is being developed to provide surgeons with objective, quantitative measurements of colon tissue quality during colorectal surgery. By providing real-time information regarding tissue mechanical properties, the technology is intended to provide objective information that may ultimately support intraoperative surgical decision-making. This may contribute over time to a better understanding of tissue properties relevant to surgical planning prior to creation of a colorectal anastomosis, and may potentially help surgeons identify patients at increased risk of developing Low Anterior Resection Syndrome (LARS).
Allen Baharaff, President and CEO of Galmed Pharmaceuticals, commented:
"The acquisition of Colospan was driven by our conviction that the company represents far more than a single-product opportunity. We recognized an innovation platform with deep scientific expertise, a differentiated technology portfolio and the ability to develop multiple solutions addressing significant unmet needs in colorectal surgery. The data we are publishing today support our belief that Colospan's engineering concepts have the potential to transition effectively into real-world clinical use. We believe that the data give Colospan a strong foundation for the continued development of the platform and support our plans to advance toward future clinical trials and regulatory submissions."
Boaz Assaf, Founder and Chief Executive Officer of Colospan, commented:
"The tissue assessment platform complements CG-100 Intraluminal Bypass Device, Colospan's investigational device designed to provide an alternative to diverting stomas following low anterior resection. Together, these technologies reflect Colospan's long-term strategy of developing innovative solutions that address critical challenges across the continuum of colorectal cancer surgery from intraoperative tissue quality assessment to postoperative healing and recovery."
About Colospan
Colospan Ltd., a wholly owned subsidiary of Galmed Pharmaceuticals Ltd. (NASDAQ: GLMD), is a commercial-stage medical device company headquartered in Kfar Saba, Israel. Its flagship product, CG-100, is an intraluminal bypass device designed to protect colorectal anastomoses and reduce the need for diverting stomas, offering a less invasive alternative to standard surgical practice. CG-100 was granted FDA Breakthrough Device Designation, is CE marked under the EU Medical Device Regulation, and is approved for investigational use in the United States under an FDA approved IDE. The device is not approved for commercial use in the US. For more information, visit www.colospan.com.
About Galmed Pharmaceuticals
Galmed Pharmaceuticals Ltd. (NASDAQ: GLMD) is an Israel-based biopharmaceutical company headquartered in Ramat Gan, with a growing focus on gastrointestinal and oncological innovation. Galmed's flagship asset, Aramchol, is a first-in-class synthetic fatty acid-bile acid conjugate molecule under evaluation across liver disease and oncological indications, including GI cancers. For more information, visit www.galmedpharma.com.
Forward-Looking Statements
Forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to risks and uncertainties that could cause our actual results to differ materially from any future results expressed or implied by the forward-looking statements. Forward-looking statements may include, but are not limited to, statements relating to the continued development, clinical evaluation and regulatory advancement of Colospan's tissue assessment platform; the potential benefits, capabilities and clinical applications of the technology; the expansion of Colospan's product pipeline; the expected benefits of Galmed's acquisition of Colospan; and Galmed's business strategy and growth plans. 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SOURCE Galmed Pharmaceuticals Ltd.